Professor Levine leads The Simons Center for Systems Biology at the Institute for Advanced Study, in Princeton, New Jersey.  The Center concentrates on research at the interface of molecular biology and the physical sciences - on genetics and genomics, polymorphisms and molecular aspects of evolution, signal transduction pathways and networks, stress responses, and pharmacogenomics in cancer biology.  His research centers on the causes of cancer.  In 1979, he and others discovered the p53 tumor suppressor protein, a molecule that inhibits tumor development.     

As chair of the National Institutes of Health Commission on AIDS Research and the National Academies Cancer Policy Board, Professor Levine has helped determine national research priorities. 

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