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Scientific Advisory Board
S. Walter Englander, Ph.D.
Edwin H. Kolodny, M.D.
William F. DeGrado, Ph.D. – Chairman of the EXSAR Scientific Advisory Board
Dr. DeGrado is the George W. Raiziss Professor of Biochemistry and
Biophysics at the University of Pennsylvania and he is a member of the
National Academy of Sciences. His published research includes
contributions to the fields of protein design, synthesis of
peptidomimetics, and characterization of membrane-active peptides.
James Broach, Ph.D.
S. Walter Englander, Ph.D.
Patrick R. Griffin, Ph.D.
Dr. Griffin is the Chairman of the Department of Molecular Therapeutics
at the Scripps Research Institute in Florida. Prior to this, Dr.
Griffin was Chief Scientific Officer & Executive Vice President of
Research at ExSAR. Previously Dr. Griffin was Senior Director in the
Basic Chemistry Department at Merck Research Laboratories. In his most
recent position at Merck, Dr. Griffin was responsible for compound
profiling and discovery phase Drug Metabolism and Pharmacokinetics
(DMPK) for the nuclear hormone receptor programs (PPARg, PPARa, GR,
LXR, FXR, and SERMS), GPCR programs (MCR-4), and protease programs
(DP-4). In addition, Dr. Griffin was a key contributor to the discovery
and development of DMP-777 (Phase IIb), a human leukocyte elastase
inhibitor.
Dr. Griffin directed a group of over 40 scientists focused on the
application of a wide-range of technologies to the drug discovery
process. He was also responsible for the development of technology to
rapidly characterize very large sets of chemical compounds and large
collections of natural products. Dr. Griffin received his Ph.D. in
Chemistry from the University of Virginia under the direction of
Professor Donald F. Hunt. In collaboration with Professor Hunt and John
R. Yates, III, Dr. Griffin was involved in the development of
biological mass spectrometry. He later researched at the California
Institute of Technology as a Postdoctoral Fellow in the laboratories of
Professor Leroy E. Hood where he was involved in systems biology.
Dr. Kolodny is the Bernard A. and Charlotte Marden Professor of Neurology and Chairman at the NYU School of Medicine. Dr. Kolodny is the vice-Chairman of the Executive Committee of the Medical Board of the Tisch Hospital, Co-Chairman of the Executive Advisory Committee of the General Clinical Research Center and Director of the Neurology Service at NYU Medical Center. His medical interests include: Neurology, Neurogenetics, Developmental Disabilities, Inborn Errors of Metabolism, and Neurodegenerative Diseases.
Don Mahuran, Ph.D.
Dr. Mahuran is presently a Senior Scientist in the Research Institute of the Hospital for Sick Children (HSC) and a Professor in the department of Laboratory Medicine and Pathobiology at the University of Toronto, Canada. His basic research carried out world wide over the last forty years has made possible the development of novel therapeutic approaches for the treatment of several of lysosomal storage diseases. He currently coordinates a group of eight Canadian researches funded by a “Team” grant from the Canadian Institutes of Health Sciences, whose goals are to develop and expand these therapeutic approaches for lysosomal storage diseases.
Company Profile (History) | Senior Management Team | Board of Directors | Scientific Advisory Board
William F. DeGrado, Ph.D. | James Broach, Ph.D. | S. Walter Englander, Ph.D. | Patrick R. Griffin, Ph.D. | Edwin H. Kolodny, M.D. | Don Mahuran, Ph.D.
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