Skip Navigation Links
Home
About Us
Therapeutic Focus
Technology
News and Publications
Careers
Contact Us
 
H/D Exchange
 
Skip Navigation LinksExSAR Home > About Us > Scientific Advisory Board
Scientific Advisory Board
 
 
 
 
 
S. Walter Englander, Ph.D.
 
 
 
 
Edwin H. Kolodny, M.D.
 
 
 





William F. DeGrado, Ph.D. – Chairman of the EXSAR Scientific Advisory Board
Dr. DeGrado is the George W. Raiziss Professor of Biochemistry and Biophysics at the University of Pennsylvania and he is a member of the National Academy of Sciences. His published research includes contributions to the fields of protein design, synthesis of peptidomimetics, and characterization of membrane-active peptides.
 
James Broach, Ph.D.
 
S. Walter Englander, Ph.D.
 
Patrick R. Griffin, Ph.D.
Dr. Griffin is the Chairman of the Department of Molecular Therapeutics at the Scripps Research Institute in Florida. Prior to this, Dr. Griffin was Chief Scientific Officer & Executive Vice President of Research at ExSAR. Previously Dr. Griffin was Senior Director in the Basic Chemistry Department at Merck Research Laboratories. In his most recent position at Merck, Dr. Griffin was responsible for compound profiling and discovery phase Drug Metabolism and Pharmacokinetics (DMPK) for the nuclear hormone receptor programs (PPARg, PPARa, GR, LXR, FXR, and SERMS), GPCR programs (MCR-4), and protease programs (DP-4). In addition, Dr. Griffin was a key contributor to the discovery and development of DMP-777 (Phase IIb), a human leukocyte elastase inhibitor.

Dr. Griffin directed a group of over 40 scientists focused on the application of a wide-range of technologies to the drug discovery process. He was also responsible for the development of technology to rapidly characterize very large sets of chemical compounds and large collections of natural products. Dr. Griffin received his Ph.D. in Chemistry from the University of Virginia under the direction of Professor Donald F. Hunt. In collaboration with Professor Hunt and John R. Yates, III, Dr. Griffin was involved in the development of biological mass spectrometry. He later researched at the California Institute of Technology as a Postdoctoral Fellow in the laboratories of Professor Leroy E. Hood where he was involved in systems biology.
 
Dr. Kolodny is the Bernard A. and Charlotte Marden Professor of Neurology and Chairman at the NYU School of Medicine. Dr. Kolodny is the vice-Chairman of the Executive Committee of the Medical Board of the Tisch Hospital, Co-Chairman of the Executive Advisory Committee of the General Clinical Research Center and Director of the Neurology Service at NYU Medical Center. His medical interests include: Neurology, Neurogenetics, Developmental Disabilities, Inborn Errors of Metabolism, and Neurodegenerative Diseases.
 

Don Mahuran, Ph.D.
Dr. Mahuran is presently a Senior Scientist in the Research Institute of the Hospital for Sick Children (HSC) and a Professor in the department of Laboratory Medicine and Pathobiology at the University of Toronto, Canada. His basic research carried out world wide over the last forty years has made possible the development of novel therapeutic approaches for the treatment of several of lysosomal storage diseases. He currently coordinates a group of eight Canadian researches funded by a “Team” grant from the Canadian Institutes of Health Sciences, whose goals are to develop and expand these therapeutic approaches for lysosomal storage diseases.









Company Profile (History) | Senior Management Team | Board of Directors | Scientific Advisory Board
William F. DeGrado, Ph.D. | James Broach, Ph.D. | S. Walter Englander, Ph.D. | Patrick R. Griffin, Ph.D. | Edwin H. Kolodny, M.D. | Don Mahuran, Ph.D.


Epitope Mapping
  Hydrogen/Deuterium Exchange Mass Spectrometry (HDMX)
 
Home   |   About Us   |   Therapeutic Focus   |   Technology   |   News and Publications   |   Careers   |   Contact Us   |   Sitemap
ExSAR is a trademark of ExSAR Corporation. Content © 2008 ExSAR Corporation. Terms of Use © 2008
11 Deer Park Drive, Suite 103   |   Monmouth Junction, New Jersey 08852   |   Phone: (732) 438-6500   |   Fax: (732) 438-1919
Optimized for resolutions of 1024 x 768 or higher with Microsoft Internet Explorer 6.0 or later
Web Site Designed and Maintained by Stonehouse Media Incorporated©