Edwin H. Kolodny, M.D.

Don Mahuran, Ph.D.

M. Maral Mouradian, M.D.

James Broach, Ph.D.

Arnold Levine, Ph.D.

William F. DeGrado, Ph.D. – Chairman of the EXSAR Scientific Advisory Board

S. Walter Englander, Ph.D.

Patrick R. Griffin, Ph.D.


Edwin H. Kolodny, M.D.
Dr. Kolodny is the Bernard A. and Charlotte Marden Professor of Neurology and Chairman at the NYU School of Medicine. Dr. Kolodny is the vice-Chairman of the Executive Committee of the Medical Board of the Tisch Hospital, Co-Chairman of the Executive Advisory Committee of the General Clinical Research Center and Director of the Neurology Service at NYU Medical Center. His medical interests include: Neurology, Neurogenetics, Developmental Disabilities, Inborn Errors of Metabolism, and Neurodegenerative Diseases.

Don Mahuran, Ph.D.
Dr. Mahuran is presently a Senior Scientist in the Research Institute of the Hospital for Sick Children (HSC) and a Professor in the department of Laboratory Medicine and Pathobiology at the University of Toronto, Canada. His basic research carried out world wide over the last forty years has made possible the development of novel therapeutic approaches for the treatment of several of lysosomal storage diseases. He currently coordinates a group of eight Canadian researches funded by a “Team” grant from the Canadian Institutes of Health Sciences, whose goals are to develop and expand these therapeutic approaches for lysosomal storage diseases.

M. Maral Mouradian, M.D.
Dr. Mouradian is currently the William Dow Lovett Professor of Neurology and Director of the Center for Neurodegenerative and Neuroimmunologic Diseases at UMDNJ-Robert Wood Johnson Medical School. Previously she served as Chief of the Genetic Pharmacology Unit at the National Institute of Neurological Disorders and Stroke (NINDS). Dr. Mouradian is the author of over 170 scholarly publications and the editor of a book on Parkinson's disease. Also, she is the recipient of the American Parkinson Disease Association Roger Duvoisin Research Scholar Award and an NIH Merit Award.

James Broach, Ph.D.
Dr. Broach is currently serving as Associate Director of the Lewis-Sigler Institute for Integrative Genomics and Professor at Princeton University, Department of Molecular Biology. He has served as an Associate Editor for the Journal Molecular and Cellular Biology and Associate Editor for the Journal Cell. He also served as Co-Chairman of the 1991 Gordon Conference on Extrachromosomal Elements and Chairman of the 1993 Gordon Conference on Plasmid and Chromosome Dynamics. Dr. Broach was on the Scientific Review Board of the Frederick Cancer Center, Co-Founder/Director of Research for Cadus Pharmaceuticals, Co-Director/Review Board Member for the Life Sciences Research Foundation.

Arnold Levine, Ph.D.
Dr. Levine was on the faculty of the Biochemistry Department of Princeton University from1968 to 1979, when he became chair and professor in the Department of Microbiology at the State University of New York, Stony Brook, School of Medicine. Returning to Princeton University in 1984, he was named Harry C. Weiss Professor in the Life Sciences in the Department of Molecular Biology, a position he held until 1998. He chaired the Department between 1984 and 1996. He was President and Chief Executive Officer of the Rockefeller University in New York City from 1998 to 2002, as well as Heilbrunn Professor of Cancer Biology and laboratory head until joining the Institute in 2002.

Dr. Levine is a graduate of Harpur College, State University of New York, and earned his PhD in microbiology from the University of Pennsylvania School of Medicine. Subsequently he was postdoctoral fellow of the Public Health Service at the California Institute of Technology. He holds honorary degrees from, among other institutions, Rider University, the University of Medicine and Dentistry of New Jersey, the Weizmann Institute of Science, and the University Pierre and Marie Curie in Paris.

The recipient of many honors, among his most recent are: the Medal for Outstanding Contributions to Biomedical Research from Memorial Sloan-Kettering Cancer Center (2000); the Keio Medical Science Prize of the Keio University Medical Science Fund, Japan (2000); the Albany Medical Center Prize in Medicine and Biomedical Research (2001); and the Award for Basic Research from the Surgical Society of Oncologists (2003).

Dr. Levine is a member of the National Academy of Sciences and of the Academy’s Institute of Medicine; he is also the author or coauthor of over 300 scientific papers, as well as a book, Viruses (1993).


William F. DeGrado, Ph.D. – Chairman of the EXSAR Scientific Advisory Board
Dr. DeGrado is the George W. Raiziss Professor of Biochemistry and Biophysics at the University of Pennsylvania and he is a member of the National Academy of Sciences. His published research includes contributions to the fields of protein design, synthesis of peptidomimetics, and characterization of membrane-active peptides.

S. Walter Englander, Ph.D.
Dr. Englander is the Jacob Gershon-Cohen Professor of Medical Science and Professor of Biochemistry and Biophysics at the University of Pennsylvania. He is a member of the National Academy of Sciences, Honorary Fellow of the Biophysical Society and Honorary Fellow of the American Association for the Advancement of Science. His work has focused on the physical processes underlying amide hydrogen exchange and models that correlate internal protein motions to the observed amide hydrogen exchange rates.

Patrick R. Griffin, Ph.D.
Dr. Griffin is the Chairman of the Department of Molecular Therapeutics at the Scripps Research Institute in Florida. Prior to this, Dr. Griffin was Chief Scientific Officer & Executive Vice President of Research at ExSAR. Previously Dr. Griffin was Senior Director in the Basic Chemistry Department at Merck Research Laboratories. In his most recent position at Merck, Dr. Griffin was responsible for compound profiling and discovery phase Drug Metabolism and Pharmacokinetics (DMPK) for the nuclear hormone receptor programs (PPARg, PPARa, GR, LXR, FXR, and SERMS), GPCR programs (MCR-4), and protease programs (DP-4). In addition, Dr. Griffin was a key contributor to the discovery and development of DMP-777 (Phase IIb), a human leukocyte elastase inhibitor.

Dr. Griffin directed a group of over 40 scientists focused on the application of a wide-range of technologies to the drug discovery process. He was also responsible for the development of technology to rapidly characterize very large sets of chemical compounds and large collections of natural products. Dr. Griffin received his Ph.D. in Chemistry from the University of Virginia under the direction of Professor Donald F. Hunt. In collaboration with Professor Hunt and John R. Yates, III, Dr. Griffin was involved in the development of biological mass spectrometry. He later researched at the California Institute of Technology as a Postdoctoral Fellow in the laboratories of Professor Leroy E. Hood where he was involved in systems biology.

Company Profile (History) | Senior Management Team | Board of Directors | Scientific Advisory Board
Edwin H. Kolodny, M.D. | Don Mahuran, Ph.D. | M. Maral Mouradian, M.D. | James Broach, Ph.D. | Arnold Levine, Ph.D. | William F. DeGrado, Ph.D. | S. Walter Englander, Ph.D. | Patrick R. Griffin, Ph.D.